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Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation
In the field of hematology, gene therapies based on integrating vectors have reached outstanding results for a number of human diseases. With the advent of novel programmable nucleases, such as CRISPR/Cas9, it has been possible to expand the applications of gene therapy beyond semi-random gene addit...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525369/ https://www.ncbi.nlm.nih.gov/pubmed/34713250 http://dx.doi.org/10.3389/fgeed.2021.618378 |