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β-Hemoglobinopathies: The Test Bench for Genome Editing-Based Therapeutic Strategies

Hemoglobin is a tetrameric protein composed of two α and two β chains, each containing a heme group that reversibly binds oxygen. The composition of hemoglobin changes during development in order to fulfill the need of the growing organism, stably maintaining a balanced production of α-like and β-li...

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Detalles Bibliográficos
Autores principales: Barbarani, Gloria, Łabedz, Agata, Ronchi, Antonella Ellena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525389/
https://www.ncbi.nlm.nih.gov/pubmed/34713219
http://dx.doi.org/10.3389/fgeed.2020.571239