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β-Hemoglobinopathies: The Test Bench for Genome Editing-Based Therapeutic Strategies
Hemoglobin is a tetrameric protein composed of two α and two β chains, each containing a heme group that reversibly binds oxygen. The composition of hemoglobin changes during development in order to fulfill the need of the growing organism, stably maintaining a balanced production of α-like and β-li...
Autores principales: | Barbarani, Gloria, Łabedz, Agata, Ronchi, Antonella Ellena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525389/ https://www.ncbi.nlm.nih.gov/pubmed/34713219 http://dx.doi.org/10.3389/fgeed.2020.571239 |
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