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Gene Correction of Point Mutations Using PolyPurine Reverse Hoogsteen Hairpins Technology

Monogenic disorders are often the result of single point mutations in specific genes, leading to the production of non-functional proteins. Different blood disorders such as ß-thalassemia, sickle cell disease, hereditary spherocytosis, Fanconi anemia, and Hemophilia A and B are usually caused by poi...

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Detalles Bibliográficos
Autores principales: Félix, Alex J., Solé, Anna, Noé, Véronique, Ciudad, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525393/
https://www.ncbi.nlm.nih.gov/pubmed/34713221
http://dx.doi.org/10.3389/fgeed.2020.583577