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Gene Correction of Point Mutations Using PolyPurine Reverse Hoogsteen Hairpins Technology
Monogenic disorders are often the result of single point mutations in specific genes, leading to the production of non-functional proteins. Different blood disorders such as ß-thalassemia, sickle cell disease, hereditary spherocytosis, Fanconi anemia, and Hemophilia A and B are usually caused by poi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525393/ https://www.ncbi.nlm.nih.gov/pubmed/34713221 http://dx.doi.org/10.3389/fgeed.2020.583577 |