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Methodologies and Challenges for CRISPR/Cas9 Mediated Genome Editing of the Mammalian Brain

Neurons and glia are highly polarized cells with extensive subcellular structures extending over large distances from their cell bodies. Previous research has revealed elaborate protein signaling complexes localized within intracellular compartments. Thus, exploring the function and the localization...

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Detalles Bibliográficos
Autores principales: Nishizono, Hirofumi, Yasuda, Ryohei, Laviv, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525404/
https://www.ncbi.nlm.nih.gov/pubmed/34713226
http://dx.doi.org/10.3389/fgeed.2020.602970