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Model Based Identification of Linezolid Exposure–toxicity Thresholds in Hospitalized Patients

Evidence supports linezolid therapeutic drug monitoring as the exposure–response relationship has been identified for toxicity among patients receiving linezolid, but the data to establish the upper limit are limited and the published toxicity thresholds range widely. The purpose of this study was t...

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Detalles Bibliográficos
Autores principales: Fang, Jie, Zhang, Xiao-Shan, Zhang, Chun-Hong, Zhou, Zi-Ye, Han, Lu, Wang, Ye-Xuan, He, Xiao-Shuang, Bian, Xiao-Lan, Lin, Guan-Yang, Jiao, Zheng, Dai, Ying, Yu, Xu-Ben, Pan, Jing-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525462/
https://www.ncbi.nlm.nih.gov/pubmed/34675806
http://dx.doi.org/10.3389/fphar.2021.732503