Modeling Site-Specific Nucleotide Biases Affecting Himar1 Transposon Insertion Frequencies in TnSeq Data Sets

TnSeq is a widely used methodology for determining gene essentiality, conditional fitness, and genetic interactions in bacteria. The Himar1 transposon is restricted to insertions at TA dinucleotides, but otherwise, few site-specific biases have been identified. As a result, most analytical approache...

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Detalles Bibliográficos
Autores principales: Choudhery, Sanjeevani, Brown, A. Jacob, Akusobi, Chidiebere, Rubin, Eric J., Sassetti, Christopher M., Ioerger, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525568/
https://www.ncbi.nlm.nih.gov/pubmed/34665010
http://dx.doi.org/10.1128/mSystems.00876-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525568/
https://www.ncbi.nlm.nih.gov/pubmed/34665010
http://dx.doi.org/10.1128/mSystems.00876-21

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