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HLA-C and KIR permutations influence chronic obstructive pulmonary disease risk

A role for hereditary influences in the susceptibility for chronic obstructive pulmonary disease (COPD) is widely recognized. Cytotoxic lymphocytes are implicated in COPD pathogenesis, and functions of these leukocytes are modulated by interactions between their killer cell Ig-like receptors (KIR) a...

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Detalles Bibliográficos
Autores principales: Mkorombindo, Takudzwa, Tran-Nguyen, Thi K., Yuan, Kaiyu, Zhang, Yingze, Xue, Jianmin, Criner, Gerard J., Kim, Young-il, Pilewski, Joseph M., Gaggar, Amit, Cho, Michael H., Sciurba, Frank C., Duncan, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525585/
https://www.ncbi.nlm.nih.gov/pubmed/34464355
http://dx.doi.org/10.1172/jci.insight.150187