Metabolic preconditioning in CD4(+) T cells restores inducible immune tolerance in lupus-prone mice

Autoimmune disease has presented an insurmountable barrier to restoration of durable immune tolerance. Previous studies indicate that chronic therapy with metabolic inhibitors can reduce autoimmune inflammation, but it remains unknown whether acute metabolic modulation enables permanent immune toler...

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Detalles Bibliográficos
Autores principales: Wilson, Christopher S., Stocks, Blair T., Hoopes, Emilee M., Rhoads, Jillian P., McNew, Kelsey L., Major, Amy S., Moore, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525586/
https://www.ncbi.nlm.nih.gov/pubmed/34403367
http://dx.doi.org/10.1172/jci.insight.143245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525586/
https://www.ncbi.nlm.nih.gov/pubmed/34403367
http://dx.doi.org/10.1172/jci.insight.143245

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