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Diminished retinal complex lipid synthesis and impaired fatty acid β-oxidation associated with human diabetic retinopathy

BACKGROUND: This study systematically investigated circulating and retinal tissue lipid determinants of human diabetic retinopathy (DR) to identify underlying lipid alterations associated with severity of DR. METHODS: Retinal tissues were retrieved from postmortem human eyes, including 19 individual...

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Detalles Bibliográficos
Autores principales: Fort, Patrice E., Rajendiran, Thekkelnaycke M., Soni, Tanu, Byun, Jaeman, Shan, Yang, Looker, Helen C., Nelson, Robert G., Kretzler, Matthias, Michailidis, George, Roger, Jerome E., Gardner, Thomas W., Abcouwer, Steven F., Pennathur, Subramaniam, Afshinnia, Farsad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525591/
https://www.ncbi.nlm.nih.gov/pubmed/34437304
http://dx.doi.org/10.1172/jci.insight.152109