IL-35 promotes CD4(+)Foxp3(+) Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms

Tregs play vital roles in suppressing atherogenesis. Pathological conditions reshape Tregs and increase Treg-weakening plasticity. It remains unclear how Tregs preserve their function and how Tregs switch into alternative phenotypes in the environment of atherosclerosis. In this study, we observed a...

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Detalles Bibliográficos
Autores principales: Shao, Ying, Yang, William Y., Saaoud, Fatma, Drummer, Charles, Sun, Yu, Xu, Keman, Lu, Yifan, Shan, Huimin, Shevach, Ethan M., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525592/
https://www.ncbi.nlm.nih.gov/pubmed/34622804
http://dx.doi.org/10.1172/jci.insight.152511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525592/
https://www.ncbi.nlm.nih.gov/pubmed/34622804
http://dx.doi.org/10.1172/jci.insight.152511

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