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IL-35 promotes CD4(+)Foxp3(+) Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms
Tregs play vital roles in suppressing atherogenesis. Pathological conditions reshape Tregs and increase Treg-weakening plasticity. It remains unclear how Tregs preserve their function and how Tregs switch into alternative phenotypes in the environment of atherosclerosis. In this study, we observed a...
Autores principales: | Shao, Ying, Yang, William Y., Saaoud, Fatma, Drummer, Charles, Sun, Yu, Xu, Keman, Lu, Yifan, Shan, Huimin, Shevach, Ethan M., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525592/ https://www.ncbi.nlm.nih.gov/pubmed/34622804 http://dx.doi.org/10.1172/jci.insight.152511 |
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