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Highly susceptible SARS-CoV-2 model in CAG promoter–driven hACE2-transgenic mice

COVID-19, caused by SARS-CoV-2, has spread worldwide with dire consequences. To urgently investigate the pathogenicity of COVID-19 and develop vaccines and therapeutics, animal models that are highly susceptible to SARS-CoV-2 infection are needed. In the present study, we established an animal model...

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Detalles Bibliográficos
Autores principales: Asaka, Masamitsu N., Utsumi, Daichi, Kamada, Haruhiko, Nagata, Satoshi, Nakachi, Yutaka, Yamaguchi, Tomokazu, Kawaoka, Yoshihiro, Kuba, Keiji, Yasutomi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525594/
https://www.ncbi.nlm.nih.gov/pubmed/34463644
http://dx.doi.org/10.1172/jci.insight.152529