Circulating bioactive bacterial DNA is associated with immune activation and complications in common variable immunodeficiency

Common variable immunodeficiency (CVID) is characterized by profound primary antibody defects and frequent infections, yet autoimmune/inflammatory complications of unclear origin occur in 50% of individuals and lead to increased mortality. Here, we show that circulating bacterial 16S rDNA belonging...

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Detalles Bibliográficos
Autores principales: Ho, Hsi-en, Radigan, Lin, Bongers, Gerold, El-Shamy, Ahmed, Cunningham-Rundles, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525635/
https://www.ncbi.nlm.nih.gov/pubmed/34622805
http://dx.doi.org/10.1172/jci.insight.144777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525635/
https://www.ncbi.nlm.nih.gov/pubmed/34622805
http://dx.doi.org/10.1172/jci.insight.144777

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