Cargando…

Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception

The mechanisms that link visceral mechanosensation to the perception of internal organ status (i.e., interoception) remain elusive. In response to bladder filling, the urothelium releases ATP, which is hypothesized to stimulate voiding function by communicating the degree of bladder fullness to subj...

Descripción completa

Detalles Bibliográficos
Autores principales: Dalghi, Marianela G., Ruiz, Wily G., Clayton, Dennis R., Montalbetti, Nicolas, Daugherty, Stephanie L., Beckel, Jonathan M., Carattino, Marcelo D., Apodaca, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525643/
https://www.ncbi.nlm.nih.gov/pubmed/34464353
http://dx.doi.org/10.1172/jci.insight.152984