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Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception
The mechanisms that link visceral mechanosensation to the perception of internal organ status (i.e., interoception) remain elusive. In response to bladder filling, the urothelium releases ATP, which is hypothesized to stimulate voiding function by communicating the degree of bladder fullness to subj...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525643/ https://www.ncbi.nlm.nih.gov/pubmed/34464353 http://dx.doi.org/10.1172/jci.insight.152984 |