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Complement factor B in high glucose–induced podocyte injury and diabetic kidney disease

The role and mechanisms for upregulating complement factor B (CFB) expression in podocyte dysfunction in diabetic kidney disease (DKD) are not fully understood. Here, analyzing Gene Expression Omnibus GSE30528 data, we identified genes enriched in mTORC1 signaling, CFB, and complement alternative pa...

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Detalles Bibliográficos
Autores principales: Lu, Qingmiao, Hou, Qing, Cao, Kai, Sun, Xiaoli, Liang, Yan, Gu, Mengru, Xue, Xian, Zhao, Allan Zijian, Dai, Chunsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525650/
https://www.ncbi.nlm.nih.gov/pubmed/34622800
http://dx.doi.org/10.1172/jci.insight.147716