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Serum circulating proteins from pediatric patients with dilated cardiomyopathy cause pathologic remodeling and cardiomyocyte stiffness

Dilated cardiomyopathy (DCM) is the most common form of cardiomyopathy and main indication for heart transplantation in children. Therapies specific to pediatric DCM remain limited due to lack of a disease model. Our previous study showed that treatment of neonatal rat ventricular myocytes (NRVMs) w...

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Detalles Bibliográficos
Autores principales: Jeffrey, Danielle A., Pires Da Silva, Julie, Garcia, Anastacia M., Jiang, Xuan, Karimpour-Fard, Anis, Toni, Lee S., Lanzicher, Thomas, Peña, Brisa, Miyano, Carissa A., Nunley, Karin, Korst, Armin, Sbaizero, Orfeo, Taylor, Matthew R.G., Miyamoto, Shelley D., Stauffer, Brian L., Sucharov, Carmen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525651/
https://www.ncbi.nlm.nih.gov/pubmed/34383712
http://dx.doi.org/10.1172/jci.insight.148637