PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting the PI3K/AKT/mTOR pathways and DNA damage repair

Radiation is an important therapeutic strategy for hepatocellular (HCC). In this study, we evaluated the role of the dual PI3K/mTOR inhibitor, PKI-587, on radiosensitization of HCC and its possible mechanism. MTT, colony formation, flow cytometry, and immunofluorescence were used to analyze the prol...

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Detalles Bibliográficos
Autores principales: Xie, Yinghai, Liu, Changwei, Zhang, Yinci, Li, Amin, Sun, Chong, Li, Rui, Xing, Yingru, Shi, Minghong, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525768/
https://www.ncbi.nlm.nih.gov/pubmed/34665844
http://dx.doi.org/10.1371/journal.pone.0258817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525768/
https://www.ncbi.nlm.nih.gov/pubmed/34665844
http://dx.doi.org/10.1371/journal.pone.0258817

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