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Deep learning allows genome-scale prediction of Michaelis constants from structural features
The Michaelis constant K(M) describes the affinity of an enzyme for a specific substrate and is a central parameter in studies of enzyme kinetics and cellular physiology. As measurements of K(M) are often difficult and time-consuming, experimental estimates exist for only a minority of enzyme–substr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525774/ https://www.ncbi.nlm.nih.gov/pubmed/34665809 http://dx.doi.org/10.1371/journal.pbio.3001402 |