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Local Renin-Angiotensin System Activation and Myofibroblast Formation in Graft Versus Host Disease–Associated Conjunctival Fibrosis

PURPOSE: The present study was designed to investigate the role of myofibroblast transdifferentiation and the conjunctival renin–angiotensin system (RAS) in the pathogenesis of graft-versus-host disease (GVHD)–associated conjunctival fibrosis. METHODS: A mouse model of major histocompatibility-match...

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Detalles Bibliográficos
Autores principales: Shamloo, Kiumars, Weng, Judy, Ross, Christopher, Lee, Jenni, Alfuraih, Saleh, Totonchy, Jennifer, Sharma, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525838/
https://www.ncbi.nlm.nih.gov/pubmed/34643664
http://dx.doi.org/10.1167/iovs.62.13.10