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Small-molecule Akt-activation in airway cells induces NO production and reduces IL-8 transcription through Nrf-2
BACKGROUND: The non-cancerous functions of Akt in the airway are understudied. In some tissues, Akt phosphorylates and activates endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO) that has anti-inflammatory effects. NO production has antibacterial and antiviral effects in the airw...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525858/ https://www.ncbi.nlm.nih.gov/pubmed/34666758 http://dx.doi.org/10.1186/s12931-021-01865-y |