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Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

A primary goal of the US National Cancer Institute's Ras initiative at the Frederick National Laboratory for Cancer Research is to develop methods to quantify RAS signaling to facilitate development of novel cancer therapeutics. We use targeted proteomics technologies to develop a community res...

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Detalles Bibliográficos
Autores principales: Whiteaker, Jeffrey R., Sharma, Kanika, Hoffman, Melissa A., Kuhn, Eric, Zhao, Lei, Cocco, Alexandra R., Schoenherr, Regine M., Kennedy, Jacob J., Voytovich, Ulianna, Lin, Chenwei, Fang, Bin, Bowers, Kiah, Whiteley, Gordon, Colantonio, Simona, Bocik, William, Roberts, Rhonda, Hiltke, Tara, Boja, Emily, Rodriguez, Henry, McCormick, Frank, Holderfield, Matthew, Carr, Steven A., Koomen, John M., Paulovich, Amanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525888/
https://www.ncbi.nlm.nih.gov/pubmed/34671754
http://dx.doi.org/10.1016/j.crmeth.2021.100015