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The conformational and mutational landscape of the ubiquitin-like marker for autophagosome formation in cancer

Macroautophagy/autophagy is a cellular process to recycle damaged cellular components, and its modulation can be exploited for disease treatments. A key autophagy player is the ubiquitin-like protein MAP1LC3B/LC3B. Mutations and changes in MAP1LC3B expression occur in cancer samples. However, the in...

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Detalles Bibliográficos
Autores principales: Fas, Burcu Aykac, Maiani, Emiliano, Sora, Valentina, Kumar, Mukesh, Mashkoor, Maliha, Lambrughi, Matteo, Tiberti, Matteo, Papaleo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525936/
https://www.ncbi.nlm.nih.gov/pubmed/33302793
http://dx.doi.org/10.1080/15548627.2020.1847443