Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein

Macroautophagy/autophagy (hereafter autophagy), the process of mass degradation of unnecessary elements within the cell, is often dysregulated in many diseases such as cancer, atherosclerosis, and neurodegenerative diseases. Hence, autophagy modulating agents have a great potential to be therapeutic...

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Detalles Bibliográficos
Autores principales: Hwang, Hui-Yun, Shim, Joong Sup, Kim, Dasol, Kwon, Ho Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525979/
https://www.ncbi.nlm.nih.gov/pubmed/33124469
http://dx.doi.org/10.1080/15548627.2020.1841953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525979/
https://www.ncbi.nlm.nih.gov/pubmed/33124469
http://dx.doi.org/10.1080/15548627.2020.1841953

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