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Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein
Macroautophagy/autophagy (hereafter autophagy), the process of mass degradation of unnecessary elements within the cell, is often dysregulated in many diseases such as cancer, atherosclerosis, and neurodegenerative diseases. Hence, autophagy modulating agents have a great potential to be therapeutic...
Autores principales: | Hwang, Hui-Yun, Shim, Joong Sup, Kim, Dasol, Kwon, Ho Jeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525979/ https://www.ncbi.nlm.nih.gov/pubmed/33124469 http://dx.doi.org/10.1080/15548627.2020.1841953 |
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