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Decreased recent adaptation at human mendelian disease genes as a possible consequence of interference between advantageous and deleterious variants
Advances in genome sequencing have improved our understanding of the genetic basis of human diseases, and thousands of human genes have been associated with different diseases. Recent genomic adaptation at disease genes has not been well characterized. Here, we compare the rate of strong recent adap...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526059/ https://www.ncbi.nlm.nih.gov/pubmed/34636724 http://dx.doi.org/10.7554/eLife.69026 |