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Modulation of fracture healing by the transient accumulation of senescent cells

Senescent cells have detrimental effects across tissues with aging but may have beneficial effects on tissue repair, specifically on skin wound healing. However, the potential role of senescent cells in fracture healing has not been defined. Here, we performed an in silico analysis of public mRNAseq...

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Detalles Bibliográficos
Autores principales: Saul, Dominik, Monroe, David G, Rowsey, Jennifer L, Kosinsky, Robyn Laura, Vos, Stephanie J, Doolittle, Madison L, Farr, Joshua N, Khosla, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526061/
https://www.ncbi.nlm.nih.gov/pubmed/34617510
http://dx.doi.org/10.7554/eLife.69958