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Innate immunity receptors in depression and suicide: upregulated NOD-like receptors containing pyrin (NLRPs) and hyperactive inflammasomes in the postmortem brains of people who were depressed and died by suicide

BACKGROUND: Abnormalities of inflammation have been implicated in the pathophysiology of depression and suicide, based on observations of increased levels of proinflammatory cytokines in the serum of people who were depressed and died by suicide. More recently, abnormalities in cytokines and innate...

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Detalles Bibliográficos
Autores principales: Pandey, Ghanshyam N., Zhang, Hui, Sharma, Anuradha, Ren, Xinguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: CMA Joule Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526128/
https://www.ncbi.nlm.nih.gov/pubmed/34588173
http://dx.doi.org/10.1503/jpn.210016