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The utility of maraviroc, an antiretroviral agent used to treat HIV, as treatment for opioid abuse? Data from MRI and behavioural testing in rats

BACKGROUND: Maraviroc is an antiretroviral agent and C-C chemokine coreceptor 5 (CCR5) antagonist that is currently used to treat human immunodeficiency virus. CCR5/μ-opioid receptor heterodimerization suggests that maraviroc could be a treatment for oxycodone abuse. We treated rats with maraviroc t...

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Detalles Bibliográficos
Autores principales: Iriah, Sade C., Borges, Catarina, Shalev, Uri, Cai, Xuezhu, Madularu, Dan, Kulkarni, Praveen P., Ferris, Craig F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: CMA Joule Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526136/
https://www.ncbi.nlm.nih.gov/pubmed/34625487
http://dx.doi.org/10.1503/jpn.200191