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Increased Toll‐like Receptor‐MyD88‐NFκB‐Proinflammatory neuroimmune signaling in the orbitofrontal cortex of humans with alcohol use disorder

BACKGROUND: Many brain disorders, including alcohol use disorder (AUD), are associated with induction of multiple proinflammatory genes. One aspect of proinflammatory signaling is progressive increases in expression across cells and induction of other innate immune genes. High‐mobility group box 1 (...

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Detalles Bibliográficos
Autores principales: Vetreno, Ryan P., Qin, Liya, Coleman, Leon G., Crews, Fulton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526379/
https://www.ncbi.nlm.nih.gov/pubmed/34415075
http://dx.doi.org/10.1111/acer.14669