Immunocompromised Cas9 transgenic mice for rapid in vivo assessment of host factors involved in highly pathogenic virus infection

Targeting host factors for anti-viral development offers several potential advantages over traditional countermeasures that include broad-spectrum activity and prevention of resistance. Characterization of host factors in animal models provides strong evidence of their involvement in disease pathoge...

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Detalles Bibliográficos
Autores principales: Collette, Nicole, Dhungel, Pragyesh, Lund, Sean J., Schwedler, Jennifer L., Saada, Edwin A., Light, Yooli K., Sinha, Anupama, Schoeniger, Joseph S., Negrete, Oscar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526419/
https://www.ncbi.nlm.nih.gov/pubmed/34729376
http://dx.doi.org/10.1016/j.omtm.2021.09.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526419/
https://www.ncbi.nlm.nih.gov/pubmed/34729376
http://dx.doi.org/10.1016/j.omtm.2021.09.012

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