Dose Effects of Histone Deacetylase Inhibitor Tacedinaline (CI-994) on Antipsychotic Haloperidol-Induced Motor and Memory Side Effects in Aged Mice

Background: Elderly patients treated with antipsychotic drugs often experience increased severity and frequency of side effects, yet the mechanisms are not well understood. Studies from our group indicate age-related histone modifications at drug targeted receptor gene promoters may contribute to th...

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Detalles Bibliográficos
Autores principales: McClarty, Bryan, Rodriguez, Guadalupe, Dong, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526546/
https://www.ncbi.nlm.nih.gov/pubmed/34690667
http://dx.doi.org/10.3389/fnins.2021.674745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526546/
https://www.ncbi.nlm.nih.gov/pubmed/34690667
http://dx.doi.org/10.3389/fnins.2021.674745

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