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SPDEF suppresses head and neck squamous cell carcinoma progression by transcriptionally activating NR4A1

SAM pointed domain containing E26 transformation-specific transcription factor (SPDEF) plays dual roles in the initiation and development of human malignancies. However, the biological role of SPDEF in head and neck squamous cell carcinoma (HNSCC) remains unclear. In this study, the expression level...

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Detalles Bibliográficos
Autores principales: Wang, Yanting, Ren, Xianyue, Li, Weiyu, Cao, Ruoyan, Liu, Suyang, Jiang, Laibo, Cheng, Bin, Xia, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526567/
https://www.ncbi.nlm.nih.gov/pubmed/34667150
http://dx.doi.org/10.1038/s41368-021-00138-0