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The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors

Schizophrenia (Scz) is a brain disorder that has a typical onset in early adulthood but otherwise maintains unknown disease origins. Unfortunately, little progress has been made in understanding the molecular mechanisms underlying neurodevelopment of Scz due to ethical and technical limitations in a...

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Detalles Bibliográficos
Autores principales: Notaras, Michael, Lodhi, Aiman, Fang, Haoyun, Greening, David, Colak, Dilek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526592/
https://www.ncbi.nlm.nih.gov/pubmed/34667143
http://dx.doi.org/10.1038/s41398-021-01664-5