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Novel implications of a strictly monomorphic (GCC) repeat in the human PRKACB gene

PRKACB (Protein Kinase CAMP-Activated Catalytic Subunit Beta) is predominantly expressed in the brain, and regulation of this gene links to neuroprotective effects against tau and Aβ-induced toxicity. Here we studied a (GCC)-repeat spanning the core promoter and 5′ UTR of this gene in 300 human subj...

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Detalles Bibliográficos
Autores principales: Khamse, Safoura, Jafarian, Zahra, Bozorgmehr, Ali, Tavakoli, Mostafa, Afshar, Hossein, Keshavarz, Maryam, Moayedi, Razieh, Ohadi, Mina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526596/
https://www.ncbi.nlm.nih.gov/pubmed/34667254
http://dx.doi.org/10.1038/s41598-021-99932-3