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Arginine metabolism and nitric oxide turnover in the ZSF1 animal model for heart failure with preserved ejection fraction

Endothelial dysfunction and altered nitric oxide (NO) metabolism are considered causal factors in heart failure with preserved ejection fraction (HFpEF). NO synthase activity depends on the availability of arginine and its derivatives. Thus, we analyzed arginine, associated metabolites, arginine-met...

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Detalles Bibliográficos
Autores principales: Büttner, Petra, Werner, Sarah, Baskal, Svetlana, Tsikas, Dimitrios, Adams, Volker, Lurz, Philipp, Besler, Christian, Knauth, Sarah, Bahls, Martin, Schwedhelm, Edzard, Thiele, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526609/
https://www.ncbi.nlm.nih.gov/pubmed/34667218
http://dx.doi.org/10.1038/s41598-021-00216-7