Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies

In a pilot study, we evaluated the feasibility of real-time deep analysis of serial tumor samples from triple negative breast cancer patients to identify mechanisms of resistance and treatment opportunities as they emerge under therapeutic stress engendered by poly-ADP-ribose polymerase (PARP) inhib...

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Detalles Bibliográficos
Autores principales: Labrie, Marilyne, Li, Allen, Creason, Allison, Betts, Courtney, Keck, Jamie, Johnson, Brett, Sivagnanam, Shamilene, Boniface, Christopher, Ma, Hongli, Blucher, Aurora, Chang, Young Hwan, Chin, Koei, Vuky, Jacqueline, Guimaraes, Alexander R., Downey, Molly, Lim, Jeong Youn, Gao, Lina, Siex, Kiara, Parmar, Swapnil, Kolodzie, Annette, Spellman, Paul T., Goecks, Jeremy, Coussens, Lisa M., Corless, Christopher L., Bergan, Raymond, Gray, Joe W., Mills, Gordon B., Mitri, Zahi I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526613/
https://www.ncbi.nlm.nih.gov/pubmed/34667258
http://dx.doi.org/10.1038/s41698-021-00232-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526613/
https://www.ncbi.nlm.nih.gov/pubmed/34667258
http://dx.doi.org/10.1038/s41698-021-00232-w

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