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Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2

Runx2 is an essential transcription factor for bone formation. Although osteocalcin, osteopontin, and bone sialoprotein are well-known Runx2-regulated bone-specific genes, the skeletal phenotypes of knockout (KO) mice for these genes are marginal compared with those of Runx2 KO mice. These inconsist...

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Detalles Bibliográficos
Autores principales: Takahata, Yoshifumi, Hagino, Hiromasa, Kimura, Ayaka, Urushizaki, Mitsuki, Kobayashi, Sachi, Wakamori, Kanta, Fujiwara, Chika, Nakamura, Eriko, Yu, Kayon, Kiyonari, Hiroshi, Bando, Kana, Murakami, Tomohiko, Komori, Toshihisa, Hata, Kenji, Nishimura, Riko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526618/
https://www.ncbi.nlm.nih.gov/pubmed/34667264
http://dx.doi.org/10.1038/s42003-021-02717-7