K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors

NKIRAS1 and NKIRAS2 (also called as κB-Ras) were identified as members of the atypical RAS family that suppress the transcription factor NF-κB. However, their function in carcinogenesis is still controversial. To clarify how NKIRAS acts on cellular transformation, we generated transgenic mice in whi...

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Detalles Bibliográficos
Autores principales: Tago, Kenji, Ohta, Satoshi, Aoki-Ohmura, Chihiro, Funakoshi-Tago, Megumi, Sashikawa, Miho, Matsui, Takeshi, Miyamoto, Yuki, Wada, Taeko, Oshio, Tomoyuki, Komine, Mayumi, Matsugi, Jitsuhiro, Furukawa, Yusuke, Ohtsuki, Mamitaro, Yamauchi, Junji, Yanagisawa, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526694/
https://www.ncbi.nlm.nih.gov/pubmed/34667224
http://dx.doi.org/10.1038/s41598-021-00200-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526694/
https://www.ncbi.nlm.nih.gov/pubmed/34667224
http://dx.doi.org/10.1038/s41598-021-00200-1

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