BRD9 inhibition promotes PUMA-dependent apoptosis and augments the effect of imatinib in gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are primarily characterized by activating mutations of tyrosine kinase or platelet-derived growth factor receptor alpha. Although the revolutionary therapeutic outcomes of imatinib are well known, the long-term benefits of imatinib are still unclear. The effec...

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Detalles Bibliográficos
Autores principales: Mu, Jianfeng, Sun, Xuezeng, Zhao, Zhipeng, Sun, Hao, Sun, Pengda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526701/
https://www.ncbi.nlm.nih.gov/pubmed/34667163
http://dx.doi.org/10.1038/s41419-021-04186-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526701/
https://www.ncbi.nlm.nih.gov/pubmed/34667163
http://dx.doi.org/10.1038/s41419-021-04186-6

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