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Structural basis of soluble membrane attack complex packaging for clearance

Unregulated complement activation causes inflammatory and immunological pathologies with consequences for human disease. To prevent bystander damage during an immune response, extracellular chaperones (clusterin and vitronectin) capture and clear soluble precursors to the membrane attack complex (sM...

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Detalles Bibliográficos
Autores principales: Menny, Anaïs, Lukassen, Marie V., Couves, Emma C., Franc, Vojtech, Heck, Albert J. R., Bubeck, Doryen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526713/
https://www.ncbi.nlm.nih.gov/pubmed/34667172
http://dx.doi.org/10.1038/s41467-021-26366-w