Glucocorticoid-Responsive Transcription Factor Krüppel-Like Factor 9 Regulates fkbp5 and Metabolism

Krüppel-like factor 9 (Klf9) is a feedforward regulator of glucocorticoid receptor (GR) signaling. Here we show that in zebrafish klf9 is expressed with GR-dependent oscillatory dynamics in synchrony with fkbp5, a GR target that encodes a negative feedback regulator of GR signaling. We found that fk...

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Detalles Bibliográficos
Autores principales: Gans, Ian M., Grendler, Janelle, Babich, Remy, Jayasundara, Nishad, Coffman, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526736/
https://www.ncbi.nlm.nih.gov/pubmed/34692682
http://dx.doi.org/10.3389/fcell.2021.727037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526736/
https://www.ncbi.nlm.nih.gov/pubmed/34692682
http://dx.doi.org/10.3389/fcell.2021.727037

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