A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes

Mutational hotspots can determine evolutionary outcomes and make evolution repeatable. Hotspots are products of multiple evolutionary forces including mutation rate heterogeneity, but this variable is often hard to identify. In this work, we reveal that a near-deterministic genetic hotspot can be bu...

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Detalles Bibliográficos
Autores principales: Horton, James S., Flanagan, Louise M., Jackson, Robert W., Priest, Nicholas K., Taylor, Tiffany B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526746/
https://www.ncbi.nlm.nih.gov/pubmed/34667151
http://dx.doi.org/10.1038/s41467-021-26286-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526746/
https://www.ncbi.nlm.nih.gov/pubmed/34667151
http://dx.doi.org/10.1038/s41467-021-26286-9

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