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A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes
Mutational hotspots can determine evolutionary outcomes and make evolution repeatable. Hotspots are products of multiple evolutionary forces including mutation rate heterogeneity, but this variable is often hard to identify. In this work, we reveal that a near-deterministic genetic hotspot can be bu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526746/ https://www.ncbi.nlm.nih.gov/pubmed/34667151 http://dx.doi.org/10.1038/s41467-021-26286-9 |