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Deficiency of SREBP1c modulates autophagy mediated lipid droplet catabolism during oleic acid induced steatosis

OBJECTIVE: Increased fatty acid and triglyceride synthesis in liver, majorly modulated by Sterol Regulator Elementing Binding Protein 1c (SREBP1c), is one of the main features of non-alcoholic fatty liver disease (NAFLD). In the present study, we aimed to identify the relation between SREBP1c and au...

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Detalles Bibliográficos
Autores principales: Sozen, Erdi, Demirel-Yalciner, Tugce, Sari, Dyana, Avcilar, Ceren, Samanci, Tuna Felix, Ozer, Nesrin Kartal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526780/
https://www.ncbi.nlm.nih.gov/pubmed/34704008
http://dx.doi.org/10.1016/j.metop.2021.100138