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HMG-Coenzyme A Reductase as a Drug Target for the Prevention of Ankylosing Spondylitis

Statins are an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR). Growing evidence indicates that statins may have an anti-inflammatory effect. Whether genetically proxied HMGCR inhibition can reduce the risk of ankylosing spondylitis is unknown. We constructed an HMGCR genetic sc...

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Detalles Bibliográficos
Autores principales: Zhong, Zhenyu, Feng, Xiaojie, Su, Guannan, Du, Liping, Liao, Weiting, Liu, Shengyun, Li, Fuzhen, Zuo, Xianbo, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526849/
https://www.ncbi.nlm.nih.gov/pubmed/34692687
http://dx.doi.org/10.3389/fcell.2021.731072