The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling

Neuropathic pain is one of the most disabling forms of chronic pain and it is characterized by hyperalgesia and allodynia linked to an aberrant processing of pain transmission and to neuroinflammation. Transforming growth factor-β1 (TGF-β1) is an anti-inflammatory cytokine, which protects against ne...

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Detalles Bibliográficos
Autores principales: Fidilio, Annamaria, Grasso, Margherita, Turnaturi, Rita, Caruso, Giuseppe, Spitale, Federica Maria, Vicario, Nunzio, Parenti, Rosalba, Spoto, Salvatore, Musso, Nicolò, Marrazzo, Agostino, Chiechio, Santina, Caraci, Filippo, Pasquinucci, Lorella, Parenti, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526862/
https://www.ncbi.nlm.nih.gov/pubmed/34690781
http://dx.doi.org/10.3389/fphar.2021.749365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526862/
https://www.ncbi.nlm.nih.gov/pubmed/34690781
http://dx.doi.org/10.3389/fphar.2021.749365

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