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Use of preclinical models for malignant pleural mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive cancer most commonly caused by prior exposure to asbestos. Median survival is 12–18 months, since surgery is ineffective and chemotherapy offers minimal benefit. Preclinical models that faithfully recapitulate the genomic and histopathological fe...

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Detalles Bibliográficos
Autores principales: Shamseddin, Marie, Obacz, Joanna, Garnett, Mathew J, Rintoul, Robert Campbell, Francies, Hayley Elizabeth, Marciniak, Stefan John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526879/
https://www.ncbi.nlm.nih.gov/pubmed/33692175
http://dx.doi.org/10.1136/thoraxjnl-2020-216602