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Atractylenolide-I Sensitizes Triple-Negative Breast Cancer Cells to Paclitaxel by Blocking CTGF Expression and Fibroblast Activation

This investigation was conducted to elucidate whether atractylenolide-I (ATL-1), which is the main component of Atractylodes macrocephala Koidz, can sensitize triple-negative breast cancer (TNBC) cells to paclitaxel and investigate the possible mechanism involved. We discovered that ATL-1 could inhi...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Li, Xue-Zhen, Zhang, Ming-Xing, Ye, Qian-Yu, Chen, Ying-Xia, Chang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526898/
https://www.ncbi.nlm.nih.gov/pubmed/34692516
http://dx.doi.org/10.3389/fonc.2021.738534